|In 1618, Powhatan died. His role was taken over by his brother, Opechancanough. Opechancanough decided to attack the colonists around Jamestown, and initially killed nearly a third of them. The English retaliated, however, and, over a ten year period, decimated the Indians. In 1608, nearly sixty thousand Indians are thought to have lived around the Chesapeake Bay area. By 1669, less than 2,000 remained.